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Using in vivo imaging to understand the immune response to infections
Welcome to our website!
We are fascinated by the immune cells of our body (white blood cells, specifically the macrophages and neutrophils) and want to understand their behaviours during infectious disease so that we can improve how they work to help us clear deadly infections such as tuberculosis. |
We are especially interested in the regulation of hypoxia signalling during TB. The above image shows fluorescently labelled white blood cells (macrophages in red and neutrophils in green) with internalised bacteria (blue). The only way to understand this properly is to watch them in action in vivo... to do this we use zebrafish models of infection. |
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